North East and North Cumbria
ICS Formulary
10 Musculoskeletal and joint diseases
10-02-02 Skeletal muscle relaxants
Baclofen
First Choice
The following baclofen intrachecal injections (
unlicensed) are also approved; 36mg in 12ml, and 72mg in 12ml intrathecal injections.
Diazepam
First Choice
Note:
diazepam 10mg tablets are no longer on the formulary.
Cannabis extract
Sativex
®
Formulary
cannabidiol 2.5mg/dronabinol 2.7mg per dose oromucosal spray
approved to treat moderate to severe spasticity in adults with multiple sclerosis in line with NICE
NENC Shared Care Protocol: Sativex (delta-9-tetrahydrocannabinol / cannabidiol) Oromucosal Spray
NICE NG144: Cannabis-based medicinal products
Dantrolene
Formulary
Tizanidine
Formulary
Approved for use on advice from neurologists when other treatments are unsuitable.
Links
Guidelines for the Management of Adults with Asymptomatic Liver Blood Test Abnormalities
NENC Shared Care Protocol: Sativex (delta-9-tetrahydrocannabinol / cannabidiol) Oromucosal Spray
NHS England Urgent Clinical Commissioning Policy Statement (170018/P)
NICE NG144: Cannabis-based medicinal products
NICE TA588: Nusinersen for treating spinal muscular atrophy
NICE TA748: Mexiletine for treating the symptoms of myotonia in non-dystrophic myotonic disorders
NICE TA755: Risdiplam for treating spinal muscular atrophy
NTAG: Transanal irrigation (TAI) systems (Peristeen Plus®, Aquaflush®, and QuFora®) for neurogenic bowel dysfunction, chronic constipation and chronic faecal incontinence
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