North East and North Cumbria
ICS Formulary
2 Cardiovascular system
02-12 Statins
MHRA Drug Safety Update (September 2023)
Statins: very infrequent reports of myasthenia gravis
Atorvastatin
First Choice
10mg, 20mg, 40mg & 80mg tablets
Rosuvastatin
Formulary
5mg, 10mg, 20mg & 40mg tablets
May be used as an alternative to atorvastatin for primary or secondary prevention in line with
NEELI
guidance
Simvastatin
Formulary
10mg, 20mg. 40mg & 80mg tablets
MHRA Drug Safety Update (Dec 2014): Simvastatin: dose limitations with concomitant amlodipine or diltiazem
Atorvastatin Chewable
Formulary
10mg and 20mg chewable tablets
Note:
atorvastatin 10mg and 20mg chewable tablets should be used instead of simvastatin suspension where solid dosage forms cannot be used.
Pravastatin
Formulary
10mg, 20mg & 40mg tablets
Links
Academic Health Science Network (North East and North Cumbria) - Atrial Fibrilation
County Durham and Darlington DVT Pathway Information
MHRA Drug Safety Update (Dec 2010): Fibrates: first-line treatment not recommended
MHRA Drug Safety Update (Dec 2010): Fibrates: first-line treatment not recommended
MHRA Drug Safety Update (Dec 2014): Simvastatin: dose limitations with concomitant amlodipine or diltiazem
MHRA Drug Safety Update (May 2014): Statins: benefits and risks
NICE NG148: Acute kidney injury: prevention, detection and management
NICE NG185: Acute coronary syndromes
NICE NG191: COVID-19 rapid guideline: managing COVID-19
NICE NG238: Cardiovascular disease: risk assessment and reduction, including lipid modification
NICE TA 733 - Inclisiran for treating primary hypercholesterolaemia or mixed dyslipidaemia
NICE TA1002 : Evinacumab for treating homozygous familial hypercholesterolaemia in people 12 years and over
NICE TA385: Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia
NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
NICE TA694 - Bempedoic acid with ezetimibe for treating primary hypercholesterolaemia or mixed dyslipidaemia
NICE TA694 - Bempedoic acid with ezetimibe for treating primary hypercholesterolaemia or mixed dyslipidaemia
NICE TA805: Icosapent ethyl with statin therapy for reducing the risk of cardiovascular events in people with raised triglycerides
Northern England Evaluation and Lipid Intensification (NEELI) Guideline
South Tees Hospitals Cardiology drug prescribing guidelines & formulary
Key
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