North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-07-04-01 Analgesics

Paracetamol
Formulary

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Ibuprofen
Formulary
Link  MHRA Drug Safety Update (June 2015): High-dose ibuprofen (≥2400mg/day): small increase in cardiovascular risk
Link  MHRA Drug Safety Update (June 2023): Non-steroidal anti-inflammatory drugs (NSAIDs): potential risks following prolonged use after 20 weeks of pregnancy

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Naproxen tablets
Formulary

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Aspirin
Formulary

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Diclofenac
Formulary
Link  MHRA Drug Safety Update (Dec 2007): NSAIDs and coxibs: balancing of cardiovascular and gastrointestinal risks
Link  MHRA Drug Safety Update (Jan 2015): Cox-2 selective inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs): Cardiovascular safety.
Link  MHRA Drug Safety Update (June 2013): Diclofenac: new contraindications and warnings
Link  MHRA Drug Safety Update (Oct 2012): Non-steroidal anti-inflammatory drugs (NSAIDs): cardiovascular risks

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