North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-09-01 Dopamine receptor agonists

Apomorphine
Formulary
  • 5mg/1ml (20ml) solution for infusion for infusion pumps & 10mg/1ml (3ml) solution for injection cartridges (Dacepton®) - NEW PATIENTS
  • 30mg/3ml solution for injection (APO-go®) - Patients commenced on treatment prior to July 2022 can continue on APO-go® (including 50mg/10ml solution for infusion pre-filled syringes for infusion pumps)
  • Apomorphine 10mg lozenges are also approved (RVI) unlicensedUnlicensed
Link  MHRA Drug Safety Update (April 2016): Apomorphine with domperidone: minimising risk of cardiac side effects
Link  NENC Shared Care Protocol - Apomorphine injection for patients within adult services with Parkinson’s disease

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Bromocriptine
Formulary

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Pramipexole
Formulary
  • Approved for second line use in Parkinson's disease. 

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Ropinirole
Formulary
  • Ropinirole once daily formulation is only approved for use in Parkinson’s disease patients with proven compliance. Green plus
  • Approved for first line use in patients with restless legs syndrome. Green

 


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Rotigotine
Formulary
  • For use on the advice of specialists in the treatment of Parkinson's disease. Mainly for use in patients who have difficulty with swallowing.
  • Approved for second line use in patients with restless legs syndrome.

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