netFormulary

North East and North Cumbria
ICS Formulary

back

5 Infections

05-03-06 COVID-19 therapeutics

Nirmatrelvir and Ritonavir Paxlovid^®

Formulary

Nirmatrelvir 150mg tablets and Ritonavir 100mg tablets (Paxlovid^®)
As per NICE TA 878

NICE TA878: Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Remdesivir Veklury^®

Restricted

100mg powder for concentrate for solution for infusion
Approved as an option for treating COVID-10 in hospitals in line with NICE:
- adults, only if they have a high risk of serious illness (risk factors as defined in section 5 of NICE's technology appraisal guidance on nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19)
- babies, children and young people, only if they:
  - are aged 4 weeks to 17 years and weigh at least 3 kg, and:
    have pneumonia, and
    
    need supplemental oxygen, or
  - weigh at least 40 kg, and have a high risk of serious illness (risk factors as defined in section 5 of NICE's technology appraisal guidance on nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID‑19).

NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19

Sotrovimab Xevudy^®

Formulary

500mg concentrate for solution for infusion

NICE TA878: Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Molnupiravir Lagevrio^®

Restricted

Molnupiravir (Lagevrio^®) 200mg capsules
Approved for FOURTH LINE use as per NHS England » Interim clinical commissioning policy: Remdesivir and molnupiravir for non-hospitalised patients with COVID-19

Casirivimab with Imdevimab Ronapreve^®

Non Formulary

Not approved for treating COVID-19 as per NICE TA878

NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Tixagevimab plus cilgavimab

Non Formulary

Not approved for treating COVID-19 as per NICE TA971

NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19

Links