North East and North Cumbria
ICS Formulary
 
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9 Nutrition and blood
09-01-04 Drugs used in autoimmune thrombocytopenic purpura

Anagrelide
Formulary
  • For the treatment of thrombocythemiaas a 2nd line agent in patients poorly/non-responsive tohydroxycarbamide therapy.

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Avatrombopag Doptelet®
Formulary
  • Approved for the treatment of severe thrombocytopenia in people with chronic liver disease needing a planned invasive procedure in line with NICE
  • Approved for treating primary chronic immune thrombocytopenia in adults in line with NICE

 

Link  NICE TA626: Avatrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure
Link  NICE TA853: Avatrombopag for treating primary chronic immune thrombocytopenia

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Caplacizumab Cablivi®
Formulary

  • 10mg solution for injection

    • Approved with plasma exchange and immunosuppression for treating acute acquired thrombotic thrombocytopenic purpura in adults, and in young people aged 12 years and over who weigh at least 40 kg in line with NICE



Link  NICE TA667: Caplacizumab with plasma exchange and immunosuppression for treating acute acquired thrombotic thrombocytopenic purpura

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Eltrombopag
Formulary
  • For the treatment of adults with chronic immune (idiopathic) thrombocytopenia purpura in line with NICE.
Link  NICE TA293: Eltrombopag for treating chronic ITP

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Lusutrombopag
Formulary

  • 3mg film-coated tablets

  • Approved as an option for treating severe thrombocytopenia in adults with chronic liver disease having planned invasive procedures in line with NICE

Link  NICE TA617: Lusutrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure

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Romiplostim
Formulary
  • For the treatment of adults with chronic immune (idiopathic) thrombocytopenia purpura in line with NICE.
Link  NICE TA221: Thrombocytopenic purpura - romiplostim

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