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 Formulary Chapter 1: Gastro-intestinal system - Full Chapter
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01.05.02  Expand sub section  Corticosteroids
Prednisolone
(Oral Preparations)
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Formulary
Green

First Choice

See BNF 06:03:02 for formulations

 

 
 
Budesonide
(Oral Preparations)
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Formulary
Green plus
  • Alternative
    • Budenofalk® (3mg capsules enclosing e/c pellets)
    • Entocort® (3mg capsules enclosing e/c m/r pellets)
    • For use on consultant gastroenterologist advice only
  • Oral Viscous Budesonide unlicensed unlicensed Red
    • For the treatment of eosinophilic oesophagitis.
    • 0.5mg or 1mg nebule is added to 13ml of syrup and this is then mixed and swallowed. 
  • Orodispersible tablet (Jorveza®) 
    • For the treatment of eosinophilic oesophagitis in adults in line with NICE Red
    • Approved for the maintenance of eosinophilic oesophagitis in line with NTAG Green plus 
  • 9mg MR tablet (Cortiment®) Red
    • For induction of remission in patients with mild to moderate active ulcerative colitis (UC) where 5-ASA treatment is not sufficient.
    • 8 week course to be provided by secondary care.
  •  4mg modified-release capsules (Kinpeygo®) Red 
    • Approved for treating primary IgA nephropathy in line with NICE
 
Link  NICE TA708 - Budesonide orodispersible tablet for inducing remission of eosinophilic oesophagitis
Link  NICE TA937: Targeted-release budesonide for treating primary IgA nephropathy
Link  NTAG Treatment Appraisal: Budesonide orodispersible (Jorveza®) for maintenance treatment of eosinophilic oesophagitis
 
Prednisolone
(Rectal Preparations)
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Formulary
Green

  • 5mg suppositories only

 
 
Budesonide
(Rectal Preparations)
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Formulary
Green

  • 2mg foam enema

  • Equal first choice with hydrocortisone foam enema  

 
 
01.05.02  Expand sub section  Oral
01.05.02  Expand sub section  Topical
01.05.02  Expand sub section  Parenteral
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Drugs for hospital use only. The responsibility for initiation and monitoring treatment should rest with an appropriate hospital clinician and the drug should be supplied through the hospital throughout the duration of treatment. In some very exceptional circumstances (e.g. due to distance from the hospital, storage, supply or mobility/transport problems) it may be appropriate for the GP to be asked to prescribe a Red drug. This should be negotiated on an individual patient basis and should only be done with the GP’s prior informed agreement where the roles of the GP and hospital services are clearly defined and agreed. The GP should not feel under pressure to prescribe in these circumstances. For all RED drugs automatically added to the formulary in response to a positive NICE TA: Prescribers need to ensure that local Trust new drug governance procedures and pharmacy processes are followed before any prescribing.  

Amber

Drugs initiated by hospital specialist, but where continuing treatment by GPs may be appropriate under a shared care arrangement. The specialist should send the GP a copy of the shared care agreement to sign. The GP should sign the shared care agreement, or indicate they do not want to be part of such an agreement, and return a copy back to the specialist. Shared care guidelines are available or are being developed for most of the drugs listed as Amber. If no shared care guideline is available, the hospital specialist should provide the patient’s GP with sufficient information and support to allow treatment to be continued and managed safely in primary care.  

Green plus

Drugs normally recommended or initiated by a specialist (hospital or GP with an extended role https://www.rcgp.org.uk/gpwer), but can be safely maintained in primary care with very little or no monitoring required. In some cases there may be a further restriction for use outlined - these will be defined in each case. Provision of additional information, or an information leaflet, may be appropriate in some cases to facilitate continuing treatment by GPs.  

Green

Drugs where prescribing by GPs is appropriate. Can be initiated and prescribed in all care settings, and if appropriate, discontinued without recourse to secondary care.  

Black

NOT APPROVED: Drugs that have been considered by NTAG or the NENC ICB Medicines Subcommittee (or other approved body) and are not approved for prescribing within the North East and North Cumbria.   

Brown

UNDER REVIEW: drugs whose current formulary status or RAG status is currently under review.  

Not Recomended

NOT REVIEWED: Drugs that haven not been reviewed yet. This usually means that an application is in progress. These drugs are not normally considered appropriate for prescribing in the North East and North Cumbria until such time that a decision is taken on their formulary status.  

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