North East and North Cumbria
ICS Formulary
 
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2 Cardiovascular system
02-05-01 Vasodilator antihypertensive drugs

Hydralazine
Formulary
  • Tablets - 25mg, 50mg

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Minoxidil
Formulary
  • Treatment should only be on the advice of a cardiologist/nephrologist.

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Diazoxide
Formulary

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Sodium nitroprusside
Formulary
  • unlicensedunlicensed import

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Ambrisentan
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. 

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Bosentan
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy.
  • Approved for systemic sclerosis with ongoing digital ulcer disease (to reduce number of new digital ulcers) - in accordance with NHS England Commissioning policy.
Link  Sildenafil and Bosentan for the Treatment of Digital Ulceration in Systemic Sclerosis

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Epoprostenol
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. 

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Hydralazine Injection
Formulary
  • Ampoules: 20mg

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Iloprost
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. 

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Macitentan
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. 

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Riociguat
Formulary
  • Approved for Chronic Thromboembolic Pulmonary Hypertension - in accordance with NHS England Commissioning policy. 

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Sildenafil
Formulary
  • 20mg tablets
  • 25mg, 50mg & 100mg tablets unlicensedunlicensed indication
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. Red
  • Approved for systemic sclerosis with ongoing digital ulcer disease (to reduce number of new digital ulcers) - in accordance with NHS England Commissioning policy. Red
  • Approved for Raynaud's Green plus

 
Link  MHRA Drug Safety Update (Nov 2018): Sildenafil (Revatio and Viagra): reports of persistent pulmonary hypertension of the newborn (PPHN) following in-utero exposure in a clinical trial on intrauterine growth restriction

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Tadalafil
Formulary
  • Approved for pulmonary hypertension in adults for whom treatment with sildenafil is not tolerated or effective (in accordance with NHS England Commissioning policy).
  • Approved for systemic sclerosis with ongoing digital ulcer disease (to reduce number of new digital ulcers) - in accordance with NHS England Commissioning policy.
  • Approved for secondary Raynaud's.

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Treprostinil
Formulary
  • Approved for pulmonary hypertension - in accordance with NHS England Commissioning policy. 

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