North East and North Cumbria
ICS Formulary
2 Cardiovascular system
02-05-05-02 Angiotensin-II receptor antagonists
Losartan
First Choice
To be used as first line treatment in all new patients.
Candesartan
Formulary
Irbesartan
Formulary
Only to be used in the treatment of exisiting patients.
Valsartan
Formulary
Only to be used in the treatment of existing patients.
Sacubitril & valsartan
Entresto
®
Formulary
Only approved for use in accordance with NICE guidance.
NICE TA388: Sacubitril valsartan for heart failure (updated 16/7/16 to include adoption resources)
Links
Academic Health Science Network (North East and North Cumbria) - Atrial Fibrilation
County Durham and Darlington DVT Pathway Information
County Durham and Tees Valley Prescribing Guideline for the Use of Anticoagulants in Non-Valvular Atrial Fibrillation
MHRA Drug Safety Update (Dec 2016): Spironolactone and renin-angiotensin system drugs in heart failure: risk of potentially fatal hyperkalaemia—clarification, December 2016
MHRA Drug Safety Update (Feb 2016): Spironolactone and renin-angiotensin system drugs in heart failure: risk of potentially fatal hyperkalaemia.
MHRA Drug Safety Update (June 2014): Combination use of medicines from different classes of renin-angiotensin system blocking agents: risk of hyperkalaemia, hypotension, and impaired renal function—new warnings
NICE ES24: COVID-19 rapid evidence summary: angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) in people with or at risk of COVID-19
NICE NG148: Acute kidney injury: prevention, detection and management
NICE NG191: COVID-19 rapid guideline: managing COVID-19
NICE TA388: Sacubitril valsartan for heart failure (updated 16/7/16 to include adoption resources)
North Cumbria - Cardiovascular workplan 2022
South Tees Hospitals Cardiology drug prescribing guidelines & formulary
Key
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