North East and North Cumbria
ICS Formulary
 
back
2 Cardiovascular system
02-09 Antiplatelet drugs

Aspirin
Formulary
  • 75mg dispersible tablets
  • Note: 75mg e/c tablets – no longer recommended for use.

Green View adult BNF  View SPC online  View childrens BNF
Cangrelor Kengrexal®
Formulary
  • 50mg powder for concentrate for solution for injection/infusion
    • Approved for bridging therapy in patients who have recently had a coronary stent but require urgent elective surgery



Red View adult BNF  View SPC online  View childrens BNF
Clopidogrel
Formulary
  • Approved for use in cardiac patients being fitted with stents/acute coronary syndromes and where aspirin is contraindicated/not tolerated, despite its use in combination with acid suppressants e.g. omeprazole.
  • Approved ischaemic stroke; in peripheral arterial/multivascular disease; or after MI only if aspirin not suitable in line with NICE.
  • The North of Tyne APC recommends the use of generic 75mg clopidogrel tablets in all the approved indications for clopidogrel.
  • Care should be taken to ensure that the brand supplied is suitable if it is to be packed into monitored dosage systems.
Link  MHRA Drug Safety Update (December 2013): Clopidogrel - risk of acquired haemophilia with clopidogrel
Link  NICE TA210: Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events

Green View adult BNF  View SPC online  View childrens BNF
Dipyridamole
Formulary
  • Only approved for use in accordance with NICE guidance.
  • 50mg in 5ml sugar free suspension alos avialable unlicensedunlicensed.
Link  NICE TA210: Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular events

Green View adult BNF  View SPC online  View childrens BNF
Prasugrel
Formulary
  • Only approved for use in accordance with NICE guidance.
Link  MHRA Drug Safety Update (January 2014): Prasugrel (Efient): increased risk of bleeding – advice around timing of loading dose for prasugrel
Link  NICE TA317 (replaces TA182): Acute coronary syndrome - prasugrel

Green plus View adult BNF  View SPC online  View childrens BNF
Ticagrelor
Formulary
  • Only approved for use in accordance with NICE guidance. 
Link  NICE TA236: Ticagrelor for the treatment of acute coronary syndromes
Link  NICE TA420: Ticagrelor for preventing atherothrombotic events after myocardial infarction

Green plus View adult BNF  View SPC online  View childrens BNF
Tirofiban
Formulary

Red View adult BNF  View SPC online  View childrens BNF
Abciximab
Formulary

Red View adult BNF  View SPC online  View childrens BNF
Aspirin 500mg in 5ml injection
Formulary
  • For specialist use in the endovascular treatment of cerebral
    aneurysms

Red View adult BNF  View SPC online  View childrens BNF
Clopidogrel 75mg in 5ml suspension
Formulary
  • Approved for use in paediatric patients with Berlin Heart devices.

Red View adult BNF  View SPC online  View childrens BNF