North East and North Cumbria
ICS Formulary
4 Central nervous system
04-02-01 First Generation Antipsychotic Drugs
Chlorpromazine
Formulary
Haloperidol
Formulary
Palliative Care
MHRA Drug Safety Update Dec 2021: Haloperidol (Haldol): reminder of risks when used in elderly patients for the acute treatment of delirium
NICE NG10: Violence and aggression: short-term management in mental health, health and community settings
TEWV Rapid Tranquilisation Policy
Perphenazine
Formulary
Sulpiride
Formulary
Zuclopenthixol
Formulary
Flupentixol
Formulary
Levomepromazine
Formulary
For use in palliative care.
Levomepromazine 25mg in 1ml injection is approved for use in palliative care.
Note:
Methotrimeprazine / Levomepromazine 6mg tablets are
unlicense
Trifluoperazine
Formulary
Links
MHRA Drug Safety Alert (Feb 2015): Drugs and driving: blood concentration limits set for certain drugs
MHRA Drug Safety Alert (Oct 2017): Clozapine: reminder of potentially fatal risk of intestinal obstruction, faecal impaction, and paralytic ileus
MHRA Drug Safety Update (Aug 2020): Clozapine and other antipsychotics: monitoring blood concentrations for toxicity
MHRA Drug Safety Update (December 2023): Aripiprazole (Abilify and generic brands): risk of pathological gambling
MHRA Drug Safety Update (Nov 2013): Risperidone and paliperidone: risk of intraoperative floppy iris syndrome in patients undergoing cataract surgery
MHRA Drug Safety Update Dec 2021: Haloperidol (Haldol): reminder of risks when used in elderly patients for the acute treatment of delirium
NENC Palliative and End of Life Care Symptom Control Guidelines
NICE CG103: Delirium
NICE CG178: Psychosis and schizophrenia in adults: prevention and management
NICE NG10: Violence and aggression: short-term management in mental health, health and community settings
NICE NG11: Challenging behaviour and learning disabilities: prevention and interventions for people with learning disabilities whose behaviour challenges
NICE NG62: Cerebral palsy in under 25s: assessment and management
NICE TA213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
NICE TA292: Bipolar disorder (children) - aripiprazole
North East and North Cumbria ICB - Clozapine supporting guidance for primary care
North of Tyne, Gateshead and North Cumbria - Antipsychotic Leaflet
NTAG - Lurasidone Treatment Appraisal: Decision Summary
TEWV - Medicines Optimisation – Interactive Guide
TEWV Guidelines
TEWV High Dose Antipsychotic Treatment (HDAT)
TEWV Rapid Tranquilisation Policy
TEWV Safe Transfer of Prescribing Guidance
Key
Full Site