North East and North Cumbria
ICS Formulary
4 Central nervous system
04-03-01 Tricyclic antidepressants
Amitriptyline
First Choice
Imipramine
Formulary
Lofepramine
Formulary
Safer than amitriptyline in overdosage, but not as effective.
Clomipramine
Formulary
Dosulepin
Non Formulary
Do not initiate for new patients and deprescribe where possible in existing patients
TEWV: Dosulepin guidance
Trimipramine
Non Formulary
Do not initiate for new patients and deprescribe where possible in existing patients
TEWV: Trimipramine deprescribing guidance
Links
MHRA Drug Safety Alert (Feb 2015): Drugs and driving: blood concentration limits set for certain drugs
NENC Palliative and End of Life Care Symptom Control Guidelines
NICE CG192: Antenatal and postnatal mental health
NICE CG61: Irritable Bowel Syndrome
NICE CG91: Depression in adults with a chronic physical health problem: recognition and management
NICE NG116: Post-traumatic stress disorder
NICE NG134: Depression in children and young people: identification and management
NICE NG206: Chronic fatigue syndrome / Myalgic encephalomyelitis
NICE NG222: Depression in adults: treatment and management
NICE NG62: Cerebral palsy in under 25s: assessment and management
TEWV - Medicines Optimisation – Interactive Guide
TEWV Depression medication pathway for adults
TEWV Guidelines
TEWV Safe Transfer of Prescribing Guidance
TEWV: Dosulepin guidance
TEWV: Trimipramine deprescribing guidance
Key
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