North East and North Cumbria
ICS Formulary
 
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5 Infections
05-03-06 COVID-19 therapeutics

Nirmatrelvir and Ritonavir Paxlovid®
Formulary
  • Nirmatrelvir 150mg tablets and Ritonavir 100mg tablets (Paxlovid®)
  • As per NICE TA 878
Link  MHRA Drug Safety Update (November 2023) : Nirmatrelvir, ritonavir (Paxlovid▼): be alert to the risk of drug interactions with ritonavir
Link  NICE TA878: Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Red View adult BNF  View SPC online  View childrens BNF
Remdesivir Veklury®
Restricted
  • 100mg powder for concentrate for solution for infusion
  • Approved as an option for treating COVID-10 in hospitals in line with NICE:
Link  NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19

Restricted Drug Red View adult BNF  View SPC online  View childrens BNF
Sotrovimab Xevudy®
Formulary
  • 500mg concentrate for solution for infusion

 

Link  NICE TA878: Casirivimab plus imdevimab, nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Red View adult BNF  View SPC online  View childrens BNF
Molnupiravir Lagevrio®
Restricted

Restricted Drug Red View adult BNF  View SPC online  View childrens BNF
Casirivimab with Imdevimab Ronapreve®
Non Formulary
  • Not approved for treating COVID-19 as per NICE TA878
Link  NICE TA878: Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19

Not Recomended View adult BNF  View SPC online  View childrens BNF
Tixagevimab plus cilgavimab
Non Formulary
  • Not approved for treating COVID-19 as per NICE TA971
Link  NICE TA971: Remdesivir and tixagevimab plus cilgavimab for treating COVID-19

Black View adult BNF  View SPC online  View childrens BNF