North East and North Cumbria
ICS Formulary
 
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6 Endocrine system
06-01-01-02 Intermediate- and long-acting insulins

Note: preloaded pens and Innolet® devices should only be used where cartridges are not suitable.


Isophane Insulin Insulatard®
Formulary
  • Approved Insulatard® formulations include:
    • 10ml vial;
    • 5x3ml cartridges (for use with Novopen® and Novopenmate® devices);
    • 5x3ml Innolet® pens. 

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Isophane Insulin Humulin® I
Formulary
  • Approved Humulin® I formulations include:
    • 10ml vials;
    • 5x3ml cartridges;
    • 5x3ml pens. 

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Insulin Glargine biosimilar Abasaglar®
Formulary
  • First choice long acting basal insulin in patients eligible for treatment in line with NICE and NTAG
  • Approved Abasaglar® formulations include:
    • 5x3ml cartridge
    • 5x3ml Kwikpen®.
Link  NG17: Type 1 diabetes in adults: diagnosis and management
Link  NTAG: Abasaglar® Insulin Glargine Biosimilar 100 units/ml for the treatment of type 1 or type 2 diabetes mellitus.

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Insulin degludec  Tresiba®
Formulary
  • 100 units/mL only
  • Pre-filled pen and cartridges
  • Approved for use in patients with Type 1 diabetes with
    • Nocturnal/Severe Hypogycaemia (with or without hypoglycaemic unawareness) in patients who would otherwsie progress to insuling pump treatment as per NICE TA151); or
    • Recurrent DKA episodes despite good compliance and who would otherwise progress to insulin pump therapy
    • Paediatric patients who cannot tolerate glargine sting
    • Paediatric patients with poor control on the high HbA1c pathway
    • Patients or Parents/Carers with unpredictable lifestyles such as students or shift workers.

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Insulin Detemir Levemir®
Formulary
  • Alternative choice long acting basal insulin.
  • Approved Levemir® formualtions include:
    • 5x3ml cartridges;
    • 5x3ml pens. 

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Insulin Glargine Lantus®
Formulary
  • Alternative choice long acting basal insulin. 
  • Approved Lantus® formulations include:
    • 10ml vials;
    • 5x3ml cartridges;
    • 5x3ml pens (Solostar® - in line with NICE). 

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Insulin Glargine  Toujeo®
Formulary
  • Alternative choice long acting basal insulin.
  • Approved Toujeo® formulations include:
    • 3x1.5ml pen (Solostar®).

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