North East and North Cumbria
ICS Formulary
 
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6 Endocrine system
06-01-02-02 Biguanides

Metformin
Formulary
  • Metformin 500mg tablets
  • Metformin 500mg oral powder sachets
  • Metformin MR (once daily - Glucophage® SR) are only approved for use in patients who have failed to tolerate the conventional tablets despite careful dose titration.
  • Note: metformin is also approved for use in Polycystic Ovary Syndrome.

 

Link  MHRA Drug Safety Update (June 2022): Metformin and reduced vitamin B12 levels: new advice for monitoring patients at risk
Link  MHRA Drug Safety Update (Mar 2022): Metformin in pregnancy: study shows no safety concerns

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